ACTIVE GRANTS

Utilizing WBCT to Evaluate PTOA Risk After ACL Reconstruction – Arthritis Foundation
01/01/2021-12/31/2023 Total Project Costs: $300,000
Donald D. Anderson, PhD and Brian R. Wolf, MD, MS Principal Investigators

3D Joint Space Width from Weight Bearing CT as an Imaging Biomarker of PTOA – Arthritis Foundation
01/01/2021-12/31/2023 Total Project Costs: $928,249
Donald D. Anderson, PhD and J. Lawrence Marsh, MD, Principal Investigators
Cesar de Cesar Netto, MD; Michael C. Willey, MD; Investigators
Univesrsity of Utah Collaborators: Justin Haller, MD; Thomas F. Higgins, MD
University of Washington Collaborators: Conor P. Kleweno, MD; Julie Agel
University of Kansas Medical Center Collaborators: Neil A.Segal, MD, MS; Bryan Vopat, MD 

Injection after Arthroscopic Partial Meniscectomy – Arthritis Foundation/Cleveland Clinic Foundation
01/01/2021-12/31/2022 Total Project Costs: $99,859
Morgan H. Jones, MD and Xiaojuan Li, MD;  Principal Investigator at the Cleveland Clinic Foundation
Donald D. Anderson, PhD, Subaward Principal Investigator

Correlating PROMIS-29 with Weight-Bearing CT Following Tibial Plafond Fracture – Orthopaedic Trauma Association/AO Trauma North America /University of Utah
01/01/2021-12/31/2022 Total Project Costs: $100,000 (UI Subaward $23,973)
Justin Haller, MD and Donald D. Anderson, PhD, Principal Investigators
J. Lawrence Marsh, MD; Michael C. Willey, MD; Thomas Higgins, MD; Conor Kleweno, MD; Julie Agel, MA; Investigators

Utilizing AI/ML Approaches to Assess Surgical Performance and Provide Virtual Coaching – Carver College of Medicine
Award: The equivalent of $15,000 provided to the Iowa Initiative for Artificial Intelligence (IIAI, www.iiai.uiowa.edu) to support the selected research project.
Donald Anderson, PhD; Geb Thomas, PhD; Stephen Baek, PhD; Matt Karam, MD; Investigators

Examining Skill Transfer from Simulation to the Operating Room for the Treatment of Pediatric Supracondylar Humerus Fractures – Carver College of Medicine Clinical and Educational Small Grant Program 
07/01/2020-06/30/2021 Total Project Costs: $15,376 
Heather Kowalski, MD, Principal Investigator
Matthew Karam, MD, Faculty Mentor
Emily Connor, MD; Geb Thomas, PhD; Steven Long, PhD;  Donald D. Anderson, PhD; Investigators

Fracture Energy Assessment Using CBCT: A Pilot Study for Predicting Risk of Post-Traumatic Craniofacial Deformities – American Association of Orthodontists Foundation 
07/01/2019-06/30/2021 Total Project Costs: $20,000
Kyungsup Shin, PhD, Principal Investigator
Thomas E. Southard, DDS, Principal Advisor
Donald D. Anderson, PhD, Research Mentor
Veeratrishul Allareddy, MS, and Xian Jin Xie, PhD, Investigators

Arthroscopic Correction of Femoroacetabular Impingement - A Joint Contact Stress Analysis – Smith & Nephew, Inc.
02/26/2019-05/31/2021 Total Project Costs: $50,999
Robert Westermann, MD, Principal Investigator
Jessica E. Goetz, PhD, Investigator

Introducing Wire Navigation Simulation to the OTA Resident Fracture Courses – Orthopaedic Trauma Association
01/01/2019-12/31/2021 Total Project Costs: $79,286
Matthew D. Karam, MD and Donald D. Anderson, PhD, Principal Investigators
Geb W. Thomas, PhD, Investigator

Translating Metabolic Responses to Mechanical Insult into Early Interventions to Prevent PTOA – Department of Defense Congressionally Directed Medical Research Programs – W81XWH-18-1-0658
09/01/2018-08/31/2022 Total Project Costs: $9,999,762
Joseph A. Buckwalter, MD, Principal Investigator

    Project 1: Small-scale early phase clinical trial of amobarbital to reduce PTOA risk in tibial pilon fractures
    Project Leads: J. Lawrence Marsh, MD and James C. Torner, PhD

    Project 2: Integrating pathomechanical PTOA risk into clinical decision-making following IAF
    Project Leads: Donald D. Anderson, PhD and Jason M. Wilken, MPT, PhD

    Project 3: Supplementing joint lubrication as an adjunct to amobarbital treatment
    Project Leads: James A. Martin, PhD and Aliasger Salem, PhD

    Project 4: Correlation of cartilage mechanics with chondrocyte mitochondrial dysfunction targeted by amobarbital
    Project Leads: Jessica E. Goetz, PhD and Mitchell C. Coleman, PhD

Benchmarking Expert Performance to Establish Competency in Wire Navigation – Orthopaedic Research and Education Foundation/American Board of Orthopaedic Surgeons
09/01/2018-08/31/2021 Total Project Costs: $300,000
Matthew D. Karam, MD and Geb W. Thomas, PhD, Principal Investigators
Donald D. Anderson, PhD,  Investigator

Accelerating Osteoarthritis Clinical Trials Through Responsive Low-Dose Standing CT Imaging – R01 AR071648
08/15/2018-06/30/2021 Total Project Costs: $606,816 (UI Subaward: $192,458)
Neil A. Segal, MD, MS Principal Investigator at University of Kansas Medical Center Research Institute, Inc.
Donald D. Anderson, PhD, Subaward Principal Investigator

The Design and Validation of a Wire Navigation Simulator for Pediatric Supracondylar Humerus Fractures – Pediatric Orthopaedic Society of North America
06/01/2018-05/31/2021 Total Project Costs: $49,701
Heather R. Kowalski, MD and Geb W. Thomas, PhD, Principal Investigators
Donald D. Anderson, PhD and Matthew D. Karam, MD, Investigators

Simulation to Support Competency-Based Training in Orthopedic Trauma – Agency for Healthcare Research and Quality R18 HS025353
09/30/2017-07/31/2022 Total Project Costs: $1,876,254
Donald D. Anderson, PhD and Geb W. Thomas, PhD, Principal Investigators
Matthew D. Karam, MD; Clarence D. Kreiter, PhD; J. Lawrence Marsh, MD, Investigators

Joint Contact Stress as a Tool for Clinical Decision Making in Periacetabular Osteotomy – Orthopaedic Research and Education Foundation
07/01/2017-06/30/2021 Total Project Costs: $209,804
Michael C. Willey, MD and Jessica E. Goetz, PhD, Principal Investigators
Donald D. Anderson, PhD, Investigator
Catherine Fruehling, BS, Research Assistant
J. Lawrence Marsh, MD, Consultant